Premium
Fetal and Maternal Velocimetry in High Risk Pregnancies for the Assessment of Adverse Perinatal Outcome
Author(s) -
GRAMELLINI D.,
FOLLI M. C.,
SACCHINI C.,
STERBINI M. P.,
LOMBARDO A.,
MERIALDI A.
Publication year - 1990
Publication title -
echocardiography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 62
eISSN - 1540-8175
pISSN - 0742-2822
DOI - 10.1111/j.1540-8175.1990.tb00408.x
Subject(s) - medicine , umbilical artery , nonstress test , middle cerebral artery , biophysical profile , obstetrics , fetus , preeclampsia , pregnancy , cerebral arteries , gestation , cardiology , heart rate , blood pressure , fetal heart rate , ischemia , genetics , biology
Pulsed‐Doppler ultrasound assessment of blood flow was performed simultaneously in the fetal middle cerebral artery, umbilical artery, and uteroplacental vessels to verify the incidence of velocimetric abnormalities, as well as their predictive value towards adverse perinatal outcome. Eighteen normal pregnancies and 32 complicated pregnancies (intrauterine growth retardation, pregnancy‐induced hypertension, chronic hypertension and pre‐eclampsia) have been examined between 30th and 40th week of gestation. Waveform abnormalities were detected even in the control group, more frequently in the cerebral artery (11.1%) and umbilical artery (5.5%) than in uteroplacental arteries. Umbilical artery abnormalities were found in intrauterine growth retardation, pregnancy‐induced hypertension, and preeclampsia; while the highest number of anomalous Doppler waveforms in the middle cerebral artery was seen in 71.4% of patients with pregnancy‐induced hypertension. Pathological umbilical artery patterns have shown a diagnostic accuracy of 62% in identifying adverse perinatal outcome. Both middle cerebral artery and uteroplacental vessels demonstrated a diagnostic accuracy of 58%. The false positive rate is 6% for the umbilical artery, 8% for the middle cerebral artery, and 0% for uteroplacental vessels, contrary to current methods of fetal surveillance (such as nonstress test, contraction stress test and biophysical profile), which have a false‐positive rate ranging from 30% to 70%.