Premium
Accuracy of Doppler Ultrasound in Evaluating Changes of Left Ventricular Diastolic Properties
Author(s) -
LIN SHOALIN,
TAK TAHIR,
KAWANISHI DAVID T.,
RAHIMTOOLA SHAHBUDIN H.,
CHANDRARATNA P. ANTHONY N.
Publication year - 1990
Publication title -
echocardiography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 62
eISSN - 1540-8175
pISSN - 0742-2822
DOI - 10.1111/j.1540-8175.1990.tb00393.x
Subject(s) - preload , cardiology , medicine , diastole , doppler effect , doppler echocardiography , hemodynamics , angiography , doppler ultrasound , ventricular pressure , blood pressure , physics , astronomy
In order to evaluate the effect of an increase in preload caused by contrast medium (Renografin‐75) on Doppler echocardiographic indices of left ventricular diastolic properties, left ventricular pressure using a catheter tip micromanometer and pulsed‐Doppler measurement of transmitral flow signals were measured simultaneously in 15 patients with coronary artery disease pre‐ and post‐left ventricular angiography. After left ventricular angiography, changes in indices determined from left ventricular pressure were significant: left ventricular end‐diastolic pressure increased from 17 ± 2 mmHg to 24 ± 2 mmHg (mean ± SE) (P < 0.001), maximum ‐dP/dt increased from 1,129 ± 63 to 1,307 ± 90 mmHg/sec (P < 0.005), and time constant decreased from 73 ± 2 to 67 ± 1 msec (P < 0.01). Changes in Doppler‐derived indices were also significant: A/E ratio decreased from 0.99 ± 0.08 to 0.81 ± 0.07 (P < 0.01), peak velocity of early diastolic filling increased from 0.61 ± 0.03 to 0.79 ± 0.03 M/sec (P < 0.01), and deceleration rate increased from 3.1 ± 0.2 to 4.6 ± 0.2 M/sec 2 (P < 0.01). Changes in Doppler echocardiographic indices (DR, acceleration half time, deceleration half time, and A/E ratio) were accompanied by changes in time constant and maximum ‐dP/dt after left ventricular angiography. However, the correlations between changes in hemodynamic indices and changes in Doppler echocardiographic indices were poor (r = 0.06 to 0.67). We conclude that changes in Doppler indices of left ventricular diastolic properties are not satisfactory for evaluating changes in left ventricular end‐diastolic pressure, time constant, and maximum ‐dP/dt which reflects the limitation of these presently available parameters to assess diastolic function.