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Ultrasonic Tissue Characterization of Normal and Ischemic Myocardium
Author(s) -
SAGAR KIRAN B.,
PELC LORIE R.,
SAEIAN KOOROUSH,
RHYNE THEODORE L.,
WANN L. SAMUEL,
WARLTIER DAVID C.
Publication year - 1990
Publication title -
echocardiography
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.404
H-Index - 62
eISSN - 1540-8175
pISSN - 0742-2822
DOI - 10.1111/j.1540-8175.1990.tb00343.x
Subject(s) - ultrasonic sensor , biomedical engineering , attenuation , characterization (materials science) , ultrasound , medicine , backscatter (email) , ischemia , ultrasonic attenuation , materials science , cardiology , radiology , computer science , optics , physics , wireless , nanotechnology , telecommunications
Cardiac ultrasonic tissue characterization is designed to use the alterations in acoustic signals from the myocardium to differentiate normal from ischemic or infarcted tissue due to their characteristic backscatter attenuation. Various approaches such as use of a gray scale, color display, or quantitative image analysis has been used for tissue characterization, but all depend on subjective assessments and are not necessarily reproducible. The most promising method has been the use of “raw” radiofrequency signals and measure changes in the ultrasonic attenuation with an index of backscatter to distinguish normal from abnormal myocardium called “integrated backscatter” (IB). Various studies have demonstrated the changes in the ultrasonic backscatter with ischemia or infarction. In this review we summarize our experience with a research prototype instrument in tissue characterization and differentiation of normal, ischemic, infarcted, and post ischemic reperfused myocardium in anesthetized open chest dogs. Currently we are investigating the role of ultrasonic tissue characterization to estimate infarct size and plan to apply these observations to patients in order to detect viable myocardium and quantitate infarct size.