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Atrial Electromechanical Interval Can Identify Patients With Paroxysmal Atrial Fibrillation and is Associated With CHADS 2 Score and Peak Velocity of Left Atrial Appendage
Author(s) -
CHAO TZEFAN,
SUNG SHIHHSIEN,
WANG KANGLING,
TSAO HSUANMING,
LIN YENNJIANG,
CHANG SHIHLIN,
LO LIWEI,
HU YUFENG,
TUAN TACHUAN,
SUENARI KAZUYOSHI,
LI CHENGHUNG,
LIU SHUENHSIN,
WU TSUJUEY,
YU WENCHUNG,
CHEN SHIHANN
Publication year - 2011
Publication title -
journal of cardiovascular electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.193
H-Index - 138
eISSN - 1540-8167
pISSN - 1045-3873
DOI - 10.1111/j.1540-8167.2011.02115.x
Subject(s) - medicine , atrial fibrillation , cardiology , paroxysmal atrial fibrillation , confidence interval , p wave
Electromechanical Interval and Paroxysmal Atrial Fibrillation . Introduction: It is difficult to discriminate patients with and without paroxysmal atrial fibrillation (PAF). The atrial electromechanical interval determined by the transthoracic echocardiogram is demonstrated to be a predictor of new onset AF. The aim of our study was to investigate whether the electromechanical interval is a useful parameter to identify patients with PAF. Methods and Results: A total of 297 patients (PAF group = 103; control group = 194) with mean age of 59.4 ± 12.4 years were enrolled. The electromechanical interval (PA‐PDI) defined as the time interval from the initiation of the P‐wave deflection to the peak of the mitral inflow A wave on the pulse‐wave Doppler imaging was measured for every patient. Patients with PAF had significantly longer PA‐PDI intervals compared with that of patients without it (152.7 ± 13.8 ms vs 133.4 ± 16.8 ms). The area under ROC curve based on the PA‐PDI interval to diagnose PAF was 0.803 (95% confidence interval = 0.755–0.851, P < 0.001). At the cut‐off value of 142 ms, the sensitivity and specificity in identifying PAF were 77.7% and 80.1%, respectively. In the PAF group, the PA‐PDI interval was closely associated with the CHADS 2 score and inversely related with the peak velocity of left atrial appendage. Conclusions: The PA‐PDI interval may be a useful parameter to identify patients with PAF. Further studies are necessary to evaluate the usefulness of PA‐PDI intervals in diagnosing PAF in addition to the current methods and tools. (J Cardiovasc Electrophysiol, Vol. 22, pp. 1325‐1330, December 2011)