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Low Risk of Major Complications Associated With Pulmonary Vein Antral Isolation for Atrial Fibrillation: Results of 500 Consecutive Ablation Procedures in Patients With Low Prevalence of Structural Heart Disease From a Single Center
Author(s) -
LEE GEOFFREY,
SPARKS PAUL B.,
MORTON JOSEPH B.,
KISTLER PETER M.,
VOHRA JITENDRA K.,
MEDI CAROLINE,
ROSSO RAPHAEL,
TEH ANDREW,
HALLORAN KAREN,
KALMAN JONATHAN M.
Publication year - 2011
Publication title -
journal of cardiovascular electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.193
H-Index - 138
eISSN - 1540-8167
pISSN - 1045-3873
DOI - 10.1111/j.1540-8167.2010.01870.x
Subject(s) - medicine , atrial fibrillation , pulmonary vein , catheter ablation , cardiology , heart disease , ablation , ablation of atrial fibrillation , cardiac tamponade , complication , surgery , tamponade , pulmonary vein stenosis
Complications Associated With Pulmonary Vein Antral Isolation for Atrial Fibrillation. Objectives : To report the major complication rate associated with pulmonary vein antral isolation (PVAI) in a consecutive series of 500 patients from a single center.Background:Catheter ablation for atrial fibrillation (AF) is an established procedure for refractory AF. However, the risk of major complications has been reported to range from 3.9% to 4.5% and continues to represent a cause for concern. We hypothesized that these studies may have overestimated the rate of major complications associated with PVAI in patients with a low prevalence of structural heart disease (SHD).Methods:Data were prospectively collected from 500 consecutive AF ablation procedures on 424 patients (mean age 55 ± 11 years, 79% men, paroxysmal AF—80% and persistent AF—20%, CHADS 2 scores of 0, 1, 2, 3 present in 64%, 28%, 7%, 1%, respectively), performed between July 2006 and September 2009. All procedures were performed under general anesthesia with intraoperative transesophageal echo. PVAI was performed using a nonfluoroscopic mapping system with an endpoint of PV isolation. Adjunctive left atrial ablation was performed in 21% of patients only. Major complications were defined from a compilation of those reported in 5 prior studies reporting complications.Results:In 500 procedures, there were no instances of death, stroke/TIA, cardiac tamponade, atrioesophageal fistula, or PV stenosis. Major complications occurred in 4 procedures (0.8%): esophageal hematoma (TEE probe)—2; pharyngeal trauma—1; and retroperitoneal hematoma—1.Conclusions:AF ablation can be performed safely in young patients without structural heart disease with a low risk (<1%) of major complications when using a strategy of PVAI. (J Cardiovasc Electrophysiol, Vol. 22, pp. 163‐168, February 2011)