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Sarcoid Myocarditis With Ventricular Tachycardia Mimicking ARVD/C
Author(s) -
LADYJANSKAIA GALINA A.,
BASSO CRISTINA,
HOBBELINK MONIQUE G.G.,
KIRKELS J. HANS,
LAHPOR JAAP R.,
CRAMER MAARTEN J.,
THIENE GAETANO,
HAUER RICHARD. N.W.,
V OOSTERHOUT MATTHIJS F.M.
Publication year - 2010
Publication title -
journal of cardiovascular electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.193
H-Index - 138
eISSN - 1540-8167
pISSN - 1045-3873
DOI - 10.1111/j.1540-8167.2009.01479.x
Subject(s) - medicine , sarcoidosis , arrhythmogenic right ventricular dysplasia , myocarditis , histopathology , endomyocardial fibrosis , ventricle , cardiomyopathy , cardiology , ventricular tachycardia , fulminant , pathology , fibrosis , heart failure
Sarcoid Myocarditis with VT Mimicking ARVD/C. Cardiac sarcoidosis (CS) is a multisystem granulomatous disorder of unknown etiology with frequent cardiac involvement. We describe a patient presenting with a ventricular tachycardia, presumably originating in the right ventricle (RV). This patient had a malignant clinical course with initial diagnosis of arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C); however, at postmortem histopathology revealed epithelioid granulomas with fibrosis localized in the interventricular septum, typical for sarcoidosis, without signs of extracardiac sarcoidosis. In conclusion, sarcoid myocarditis may present with signs and symptoms of ARVD/C and only histopathology can differentiate the 2 diseases. In the cases of atypical clinical presentation or when histopathological proof of ARVD is absent, a close follow‐up is advisable to identify other potentially treatable disorders. (J Cardiovasc Electrophysiol, Vol. 21, pp. 94–98, January 2010)