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“Left‐Variant” Atypical Atrioventricular Nodal Reentrant Tachycardia: Electrophysiological Characteristics and Effect of Slow Pathway Ablation within Coronary Sinus
Author(s) -
OTOMO KIYOSHI,
OKAMURA HIDEO,
NODA TAKASHI,
SATOMI KAZUHIRO,
SHIMIZU WATARU,
SUYAMA KAZUHIRO,
KURITA TAKASHI,
AIHARA NAOHIKO,
KAMAKURA SHIRO
Publication year - 2006
Publication title -
journal of cardiovascular electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.193
H-Index - 138
eISSN - 1540-8167
pISSN - 1045-3873
DOI - 10.1111/j.1540-8167.2006.00598.x
Subject(s) - medicine , coronary sinus , ablation , cardiology , tachycardia , electrophysiology study , nodal , electrophysiology , atrioventricular node , ostium , eccentric , nodal signaling , reentry , catheter ablation , chemistry , gastrulation , biochemistry , physics , embryonic stem cell , quantum mechanics , gene
Recent anatomical and electrophysiological studies have demonstrated the presence of leftward posterior nodal extension (LPNE); however, its role in the genesis of atrioventricular nodal reentrant tachycardia (AVNRT) is poorly understood. This study was performed to characterize successful slow pathway (SP) ablation site and to elucidate the role of LPNE in genesis of atypical AVNRT with eccentric activation patterns within the coronary sinus (CS). Methods and Results: Among 45 patients with atypical AVNRT (slow‐slow/fast‐slow/both = 20/22/3 patients) with concentric (n = 37, 82%) or eccentric CS activation (n = 8, 18%), successful ablation site was evaluated. Among 35/37 patients (95%) with concentric CS activation, ablation at the conventional SP region outside CS eliminated both retrograde SP conduction and AVNRT inducibility. Among eight patients with eccentric CS activation, the earliest retrograde atrial activation was found at proximal CS 16 ± 4 mm distal to the ostium during AVNRT. The earliest retrograde activation site was located at inferior to inferoseptal mitral annulus, consistent with the presumed location of LPNE. Ablation at the conventional SP region with electroanatomical approach only rendered AVNRT nonsustained without elimination of retrograde SP conduction in seven of eight patients (88%). Ablation targeted to the earliest retrograde atrial activation site within proximal CS (15 ± 4 mm distal to the ostium); however, eliminated retrograde SP conduction and rendered AVNRT noninducible in six of eight patients (75%). Conclusion: In 75% of “left‐variant” atypical AVNRT, ablation within proximal CS was required to eliminate eccentric retrograde SP conduction and render AVNRT noninducible, suggesting LPNE formed retrograde limb of reentrant circuit.