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Monomorphic Ventricular Tachycardia Due to Brugada Syndrome Successfully Treated by Hydroquinidine Therapy in a 3‐Year‐Old Child
Author(s) -
PROBST VINCENT,
EVAIN STEPHANE,
GOURNAY VERONIQUE,
MARIE ALLOUIS,
SCHOTT JEANJACQUES,
BOISSEAU PIERRE,
LE MAREC HERVE
Publication year - 2006
Publication title -
journal of cardiovascular electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.193
H-Index - 138
eISSN - 1540-8167
pISSN - 1045-3873
DOI - 10.1111/j.1540-8167.2005.00329.x
Subject(s) - brugada syndrome , medicine , cardiology , ventricular fibrillation , ventricular tachycardia , implantable cardioverter defibrillator , tachycardia
Mutations in the SCN5A gene can cause Brugada syndrome, a genetically inherited form of idiopathic ventricular fibrillation. We describe the case of a 3‐year‐old child with a structurally normal heart presenting with monomorphic ventricular tachycardia. Her electrocardiogram suggested a Brugada syndrome and the diagnosis was confirmed by the identification of a Brugada syndrome in her mother and in two other family members. Genetic study led to the identification of a c.2516T→C SCN5A mutation. The child was treated with quinidine therapy without recurrence of arrhythmic events for a time period of 16 months.