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Prevention of Ventricular Fibrillation by Pacing in a Man with Brugada Syndrome
Author(s) -
LEE KATHY L.,
LAU CHUPAK,
TSE HUNGEAT,
WAN SIUHONG,
EAN KATHERINE
Publication year - 2000
Publication title -
journal of cardiovascular electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.193
H-Index - 138
eISSN - 1540-8167
pISSN - 1045-3873
DOI - 10.1111/j.1540-8167.2000.tb00076.x
Subject(s) - brugada syndrome , medicine , ventricular fibrillation , cardiology , implantable cardioverter defibrillator , fibrillation , sudden cardiac death , atrial fibrillation
Pacing Prevents VF in Brugada Syndrome. The unique ECG appearance of Brugada syndrome is caused by failure of the dome of the action potential to develop. It occurs when the outward currents (mainly I to ) overwhelm the inward currents (mainly I ca ) at the end of phase 1 of the action potential. Because I to becomes less prominent at a faster rate, increased heart rate is associated with decreased ST segment elevation on ECG and probably decreased incidence of ventricular arrhythmia. We present the first report on prevention of ventricular fibrillation in a man with Brugada syndrome by overdrive pacing from his dual chamber implantable cardioverter defibrillator.