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Congenital Disorders of Cardiac Rhythm and Conduction
Author(s) -
JAMES THOMAS N.
Publication year - 1993
Publication title -
journal of cardiovascular electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.193
H-Index - 138
eISSN - 1540-8167
pISSN - 1045-3873
DOI - 10.1111/j.1540-8167.1993.tb01256.x
Subject(s) - medicine , cardiology , electrical conduction system of the heart , fibromuscular dysplasia , brugada syndrome , sudden cardiac death , left bundle branch block , atrial fibrillation , electrocardiography , heart failure , renal artery , kidney
Congenital Arrhythmias and Heart Block. Electrical instability of the heart has numerous congenital origins. This review approaches the problems from a morphological standpoint, utilizing selected examples from my own studies of the human cardiac conduction system performed during the last three decades. Subjects discussed include multifocal Purkinje cell tumors, benign congenital polycystic tumors of the AV node, several types of congenital heart hlock, postnatal morphogenesis of the AV node and His bundle (including considerations of persistent fetal dispersion and crib death), the Wolff‐Parkinson‐White syndrome, left superior vena cava, focal fibromuscular dysplasia of small coronary arteries, hereditary neuromus‐cular or musculoskeletal diseases, familial atrial fibrillation, long QT syndrome, and apoptosis of the heart. In many congenital disorders of cardiac electrical activity, both arrbythmias and conduction disturbances may occur. How the abnormal anatomy may relate to cardiac electrical instahility is discussed, including certain clinical matters to he considered.