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Propafenone Therapy in Patients with Serious Ventricular Arrhythmia ‐ Noninvasive Evaluation of Efficacy
Author(s) -
CUENI LAWRENCE,
PODRID PHILIP J.
Publication year - 1987
Publication title -
journal of electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.193
H-Index - 138
eISSN - 1540-8167
pISSN - 0892-1059
DOI - 10.1111/j.1540-8167.1987.tb01447.x
Subject(s) - propafenone , medicine , exacerbation , cardiology , drug , adverse effect , cardiac arrhythmia , anti arrhythmia agents , anesthesia , pharmacology , atrial fibrillation
Propafenone is a newv IC antiarrhythmic agent that is effective for suppression of spontaneously occurring ventricular arrhythmia as evauated with monitoring and exercise testing. The incidence of nonserious, but disturbing side effects is low and the drug infrequently is discontinued because of adverse reactions. Serious side effects are primarily cardiac and include arrhythmia aggravation, CHF exacerbation, and conduction abnormalities. These complications occur primarily in those with severe underlying heart disease in whom this drug, like other antiarrhythmic agents, must be used cautiously. If the drug is effective and well tolerated, arrhythmia recurrence can be prevented.