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Flecainide Suppresses Defibrillator‐Induced Storming in Catecholaminergic Polymorphic Ventricular Tachycardia
Author(s) -
HONG ROBERT A.,
RIVERA KAHEALANI K.,
JITTIRAT ARKSARAPUK,
CHOI JOON J.
Publication year - 2012
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/j.1540-8159.2012.03421.x
Subject(s) - medicine , flecainide , catecholaminergic polymorphic ventricular tachycardia , ventricular tachycardia , cardiology , anesthesia , atrial fibrillation , ryanodine receptor 2 , ryanodine receptor , calcium
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited condition associated with ventricular tachycardia (VT) triggered by exercise or sympathetic stress. Incessant VT may develop due to defibrillator‐induced storming—a condition where implantable cardioverter‐defibrillator discharges result in a hyperadrenergic state, provoking further VT and defibrillator discharge. We describe the case of a 14‐year‐old boy with CPVT caused by a calsequestrin‐2 mutation, who presented with defibrillator‐induced storming refractory to β‐blockers, calcium‐channel blockers, amiodarone, and dronedarone. Flecainide and β‐blocker use suppressed incessant VT and defibrillator‐induced storming. (PACE 2012;XX:e1–e4)