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Computer Simulation of Clinical Electrophysiological Study
Author(s) -
ZHU XIN,
WEI DAMING,
OKAZAKI OSAMU
Publication year - 2012
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/j.1540-8159.2012.03379.x
Subject(s) - medicine , electrophysiology , tachycardia , reentry , cardiology , supraventricular tachycardia , antidromic , cardiac electrophysiology , intracardiac injection , wpw syndrome , accessory pathway , electrophysiology study , ventricular tachycardia , atrial fibrillation , catheter ablation
Background:Computer simulation is an important method for the basic researches of cardiac electrophysiology to prove the mechanisms and hypotheses of cardiac arrhythmias by reproducing body surface electrocardiograms. In this research, we extend the researches of heart models to the computer simulation of clinical electrophysiological study (EPS) as a clinical application of heart models.Method:Through setting the standard EPS pacing protocols, including extrastimuli and incremental pacing in the heart models, we simulated the corresponding excitation propagations in the heart and the intracardiac electrograms that would be measured with catheter electrodes.Results:Examples of complicated cases observed during EPS are reproduced in this research, including the induction of a Wenckebach pattern, the induction and termination of supraventricular tachycardia due to the reentry loop of antidromic atrioventricular reentrant tachycardia for the Wolff‐Parkinson‐White (WPW) syndrome (Type A), and the localization of an accessory pathway for the WPW syndrome (Type A) .Conclusion:This study demonstrates an application of whole‐heart modeling and computer simulation to clinical EPS. (PACE 2012; 35:718–729)