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The Hemodynamic Effect of Right Ventricle (RV), RT3DE Targeted Left Ventricle (LV) and Biventricular (BIV) Pacing in the Early Postoperative Period After Cardiac Surgery
Author(s) -
STRAKA FRANTISEK,
PIRK JAN,
PINDAK MARIAN,
SKALSKY IVO,
VANCURA VLASTIMIL,
CIHAK ROBERT,
MAREK TOMAS,
LUPINEK PETR,
MASIN JAROSLAV,
SCHORNIK DAVID,
ZEMAN MICHAL,
SKROBAKOVA JANKA,
DORAZILOVA ZORA,
SKIBOVA JELENA
Publication year - 2011
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/j.1540-8159.2011.03161.x
Subject(s) - medicine , ventricle , cardiology , cardiac resynchronization therapy , ejection fraction , heart failure , hemodynamics , cardiac surgery , qrs complex
Background: Congestive heart failure negatively impacts the prognosis in patients after cardiac surgery. The aim of our study was to assess the value of targeted cardiac resynchronization therapy (CRT) within 72 hours after cardiac surgery in patients with mechanical dyssynchrony, who had an ejection fraction ≤ 35%, QRS ≥150 ms or between 120 and 150 ms.Methods: A prospective randomized trial based on three‐dimensional echocardiography (RT3DE) and optimized sequential dual‐chamber (DDD) pacing in patients after cardiac surgery. DDD epicardial pacing (Medtronic coaxial epicardial leads 6495) was provided by a modified Medtronic INSYNC III Pacemaker (Medtronic Inc., Minneapolis, MN, USA).Summary of results: The study included 21 patients with ischemic heart disease (HD) or valvular HD (16 men, 5 women, average age 69 years) with left ventricle (LV) dysfunction after cardiac surgery. Patients with biventricular (BIV) (CO 6.7 ± 1.7 L/min, CI 3.5 ± 0.8 L/min/m 2 ) and LV (CO 6.2 ± 1.5 L/min, CI 3.2 ± 0.7 L/min/m 2 ) pacing had statistically significantly higher CO and CI than patients with right ventricular (RV) (CO 5.4 ± 1.4 L/min, CI 2.8 ± 0.6 L/min/m 2 ) pacing (BIV vs RV P ≤ 0.001; LV vs RV P ≤ 0.05; BIV vs LV P ≤ 0.05).Conclusions: RT3DE targeted and optimized CRT in the early postperative period after cardiac surgery provided better hemodynamic results than RV pacing. (PACE 2011; 34:1231–1240)