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Flecainide‐Associated Bradycardia‐Dependent Torsade de Pointes: Another Potential Mechanism of Proarrhythmia
Author(s) -
KIM HAN SANG,
PAK HUINAM,
PARK JONG SEOUNG,
KIM SUNG SOON
Publication year - 2013
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/j.1540-8159.2010.02935.x
Subject(s) - proarrhythmia , flecainide , medicine , bradycardia , cardiology , anesthesia , tachycardia , ventricular tachycardia , long qt syndrome , atrial tachycardia , qt interval , heart rate , atrial fibrillation , catheter ablation , blood pressure
Although flecainide has a risk of proarrhythmia in patients with structural heart disease, its mechanism has been mainly ascribed to use‐dependency and a rapid ventricular response to organized atrial tachyarrhythmias or to ventricular tachycardia. We present a patient who experienced recurrent syncope due to bradycardia‐dependent torsade de pointes (TdP) associated with flecainide‐related bradycardia and QT prolongation. Bradycardia‐dependent TdP with QT prolongation can be considered as one of mechanisms of flecainide‐induced proarrhythmia.