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Electrical Storm in Brugada Syndrome during Pregnancy
Author(s) -
SHARIFKAZEMI MOHAMMAD B.,
EMKANJOO ZAHRA,
TAVOOSI AMIR,
KAFI MOHAMMAD,
KHEIRKHAH JALAL,
ALIZADEH ABOLFATH,
SADRAMELI MOHAMMAD A.
Publication year - 2011
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/j.1540-8159.2010.02740.x
Subject(s) - brugada syndrome , medicine , pregnancy , quinidine , pathogenesis , cardiology , biology , genetics
Clinical and molecular characterization of the Brugada syndrome has progressed rapidly since its initial description. The role of hormonal changes during pregnancy and postpartum period on the pathogenesis of Brugada syndrome has not been studied. Herein, we describe a case of revelation of Brugada syndrome during pregnancy in a young woman who presented with electrical storm as the first manifestation. Low‐dose isoproterenol infusion followed by oral quinidine inhibited the recurrence of ventricular tachyarrhythmia and normalized the electrocardiographic pattern. We emphasize the importance of hormonal changes during pregnancy as a precipitating factor for arrhythmic events in Brudaga syndrome. (PACE 2011; 34:e18–e21)