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Cardiac Memory Induced by QRS Widening due to Propafenone Toxicity
Author(s) -
WYLIE JOHN V.,
ZIMETBAUM PETER,
JOSEPHSON MARK E.,
SHVILKIN ALEXEI
Publication year - 2007
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/j.1540-8159.2007.00830.x
Subject(s) - propafenone , medicine , qrs complex , cardiology , toxicity , precordial examination , cardiac toxicity , electrocardiography , atrial fibrillation
Propafenone toxicity can cause significant QRS widening and markedly abnormal ventricular activation pattern. Aberrant ventricular activation upon its resolution is known to produce persistent T‐wave changes known as “cardiac memory” (CM). A 74‐year‐old woman presented with a severely abnormal electrocardiogram consistent with propafenone toxicity. As her QRS complex narrowed, T‐wave inversions developed with the T‐wave axis and resolution kinetics consistent with CM. Abnormal ventricular activation due to propafenone toxicity can result in CM development.