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Brugada Type Electrocardiographic Changes Induced by Concomitant Use of Lithium and Propafenone in Patient with Wolff–Parkinson–White Syndrome
Author(s) -
FRAGAKIS NIKOLAOS,
ILIADIS ILIAS,
PAPANASTASIOU SOULTANA,
LAMBROU ALEXANDRA,
KATSARIS GEORGE
Publication year - 2007
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/j.1540-8159.2007.00762.x
Subject(s) - propafenone , medicine , brugada syndrome , cardiology , precordial examination , concomitant , lithium (medication) , electrocardiography , anesthesia , atrial fibrillation
We report a case of ST elevation in right precordial leads compatible with type 1 Brugada syndrome following administration of propafenone in a patient with Wolff–Parkinson–White syndrome who was receiving lithium at concentrations within therapeutic levels. The mechanism of the electrocardiogram changes was considered to be caused by the two drugs synergistic sodium channel blocking effects .