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Multiple Premature Beats Triggered Ventricular Arrhythmias During Pilsicainide Infusion in a Patient with Inferior ST‐Segment Elevation
Author(s) -
CHINUSHI MASAOMI,
IZUMI DAISUKE,
FURUSHIMA HIROSHI,
WATANABE HIROSHI,
AIZAWA YOSHIFUSA
Publication year - 2006
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/j.1540-8159.2006.00562.x
Subject(s) - medicine , cardiology , st segment , ventricular tachycardia , brugada syndrome , atrial flutter , st elevation , electrocardiography , anesthesia , myocardial infarction , atrial fibrillation
A 17‐year‐old man was referred to our hospital for treatment of common paroxysmal atrial flutter. His electrocardiogram at rest showed subtle ST‐segment elevation in leads II, III, and aV F . Intravenous pilsicainide caused further ST‐segment elevation in the inferior leads, new ST‐segment depression in leads V2–V6, two distinct forms of premature ventricular complexes (PVCs) triggering short runs of polymorphic ventricular tachycardia (VT). An infusion of isoproterenol suppressed these arrhythmias and normalized the ST‐segment. Pilsicainide may induce PVCs and polymorphic VT in atypical Brugada syndrome.