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Prevalence and Clinical Course of the Juveniles with Brugada‐Type ECG in Japanese Population
Author(s) -
OE HIROKI,
TAKAGI MASAHIKO,
TANAKA ATSUSHI,
NAMBA MASASHI,
NISHIBORI YOSHIHARU,
NISHIDA YUKIO,
KAWARABAYASHI TAKAHIKO,
YOSHIYAMA MINORU,
NISHIMOTO MASAKI,
TANAKA KUMEO,
YOSHIKAWA JUNICHI
Publication year - 2005
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/j.1540-8159.2005.40020.x
Subject(s) - brugada syndrome , medicine , j wave , st elevation , population , cardiology , st segment , sudden cardiac death , precordial examination , pediatrics , electrocardiography , myocardial infarction , environmental health
Background: Although many studies on Brugada syndrome have been done, with many reports of genetic findings and clinical features, little evidence exists to support the role of this syndrome in sudden cardiac death in a juvenile population. We sought to determine the prevalence and clinical course in children exhibiting Brugada‐type ECG in a community‐based population.Methods: Our study population comprised 21,944 subjects (11,282 boys and 10,662 girls) who underwent ECG during their first‐year elementary school health examinations between 1992 and 2001 in Izumi City, Osaka. Brugada‐type ECG was defined as demonstrating ST‐segment elevation (coved or saddle‐back type, J wave amplitude ≥0.2 mV) in the right precordial leads. We also divided Brugada‐type ECGs into three types according to a consensus report. Type 1: coved ST‐segment elevation displaying high J wave amplitude followed by a negative T wave; Type 2: high take‐off and gradually descending ST‐segment elevation (remaining ≥1 mm) followed by a positive or biphasic T wave; and Type 3: ST‐segment elevation of <1 mm of both types.Results: Four subjects showed Brugada‐type ECG (0.02%) (2 boys and 2 girls). Only one subject, a girl, met Type 1 criteria (0.005%). No history of structural heart disease was documented in these four subjects. During 6.8 ± 1.0 years of follow‐up, no episode of unexpected sudden death, syncopal attack, and fatal arrhythmia occurred.Conclusions: The prevalence of Brugada‐type ECG in a juvenile population was extremely low. To investigate when the typical Brugada‐type ECG might be manifested, it could be necessary to check ECGs after adolescence.