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Isotretinoin (13‐ Cis ‐Retinoic Acid) Associated Atrial Tachycardia
Author(s) -
HASDEMIR CAN,
SAGCAN ABDI,
SEKURI CEVAT,
ILDIZLI MUGE,
ULUCAN CEM,
CEYLAN CAN
Publication year - 2005
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/j.1540-8159.2005.09365.x
Subject(s) - medicine , palpitations , isotretinoin , asymptomatic , discontinuation , tachycardia , atrial fibrillation , cardiology , anesthesia , acne , dermatology
We describe a 16‐year‐old boy who presented with palpitations for 1 week while being on isotretinoin treatment for nodulocystic facial acne for 3 months. Twenty four‐hour Holter monitoring showed frequent premature atrial beats and episodes of nonsustained atrial tachycardia. He never had any episodes of palpitations previously. His complaints almost disappeared within a week after stopping the treatment. He remained asymptomatic since the discontinuation of the drug. The temporal relationship between isotretinoin treatment and patient's symptoms in the presence of documented arrhythmia suggests a drug‐related cause. As a result, clinicians should be aware of the possible arrhythmogenic effect of isotretinoin.