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Enhanced Rate Response Algorithm for Orthostatic Compensation Pacing
Author(s) -
MAI JUNYU,
PARK EULJOON,
BORNZIN GENE A.,
HAUCK GREG,
LEVINE PAUL A.
Publication year - 2000
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/j.1540-8159.2000.tb07025.x
Subject(s) - medicine , orthostatic vital signs , cardiac pacing , algorithm , compensation (psychology) , heart rate , cardiology , blood pressure , psychoanalysis , computer science , psychology
Upon orthostatic stress after a period of rest, the heart rate increases rapidly to maintain cardiac output and minimize the fall in arterial pressure. Pacemaker patients are often prone to a deficient response to orthostatic stress. This may cause lightheadedness and, in rare patients with autonomic dysfunction, syncope. To alleviate these undesirable consequences, an enhanced rate response algorithm was developed using an accelerometer. The pacemaker generates two signals from its accelerometer: instantaneous activity level (Act) and long‐term change in activity level (ActVar). Low values of both Act and ActVar indicate a resting state. An increase in Act while ActVar remains low indicates the onset of motion after prolonged rest. Upon detecting this transition, the algorithm increases the pacing rate to a programmable orthostatic compensation rate for a programmable duration. A taped‐on pacemaker with this algorithm was evaluated in three healthy women and two healthy men, 36 ± 8 years of age. Electrocardiogram and ventricular pacing pulses were recorded by a 24‐hour ambulatory system. Each trigger of the orthostatic compensation rate was verified against a >10 beats/min increase in heart rate, a response classified as appropriate. The overall specificity of the algorithm among the five subjects was 78%. The nocturnal specificity (10 pm to 7 am) was 98%, considerably higher than during daytime (72%). In conclusion, a pacing algorithm to alleviate orthostatic stress was developed, which was highly specific during the night hours.