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Advantages and Disadvantages of Trial Designs : A Review of Analysis Methods for ICD Studies
Author(s) -
HALLSTROM ALFRED P.,
ANDERSON JEFFREY L.,
COBB LEONARD A.,
FRIEDMAN PETER L.,
HERRE JOHN M.,
KLEIN RICHARD C.,
MCANULTY JOHN,
STEINBERG JONATHAN S.
Publication year - 2000
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/j.1540-8159.2000.tb00892.x
Subject(s) - medicine , modalities , randomized controlled trial , selection (genetic algorithm) , treatment modality , medical physics , intensive care medicine , artificial intelligence , surgery , social science , sociology , computer science
General modalities of analyses that have, been used for ICD studies are reviewed. Published “typical” examples are briefly described. The historical cohort method is exemplified with previously unpublished data from the Seattle Cardiac Arrest Survivor database. The AVID Study database is used to compare the results obtained from nonrandomized methodologies with randomized methodologies. Particular issues related to the use of the ICD for example, mode of death, inability to blind, selection practice, and treatment decision times make this a natural pedagogic platform.