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Autonomic Nervous System Activity Before and During Episodes of Myocardial Ischemia in Patients with Stable Coronary Artery Disease During Daily Life
Author(s) -
KOCHIADAKIS GEORGE E.,
MARKETOU MARIA E.,
IGOUMENIDIS NIKOS E.,
SIMANTIRAKIS EMMANUEL N.,
PARTHENAKIS FRAGISKOS I.,
MANIOS EMMANUEL G.,
VARDAS PANOS E.
Publication year - 2000
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/j.1540-8159.2000.tb00772.x
Subject(s) - medicine , cardiology , coronary artery disease , autonomic nervous system , nocturnal , heart rate variability , disease , heart rate , blood pressure
Spectral analysis of heart rate variability (HR V) was used to assess changes in the autonomic nervous system (ANS) 10 minutes before, during, and 10 minutes after 110 ischemic episodes (IEs) in 38 patients (25 men, age 61 ± 10 years) with stable coronary artery disease. In 26 of 77 diurnal IEs (07:00–22:59) there were no changes in the spectral indexes (LF and HF) during the study period. In the remainder there was an increase in the LF:HF ratio due to HF withdrawal that started before the onset of the IE. AII 33 nocturnal episodes also showed an increase in the LF:HF ratio, which was due not only to HF withdrawal, but also to a simultaneous increase in LF. Although it is not the only cause, the ANS plays a significant role in triggering IEs during daily life in patients with stable coronary artery disease. The common factor in all such episodes is a gradual withdrawal of parasympathetic tone.