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Torsade de Pointes Ventricular Tachycardia During Low Dose Intermittent Dobutamine Treatment in a Patient with Dilated Cardiomyopathy and Congestive Heart Failure
Author(s) -
VECCHIA LUIGI,
OMETTO RENATO,
FINOCCHI GIUSEPPE,
VINCENZI MARIO
Publication year - 1999
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/j.1540-8159.1999.tb00461.x
Subject(s) - medicine , cardiology , heart failure , dobutamine , ventricular tachycardia , dilated cardiomyopathy , cardiomyopathy , hemodynamics
The authors describe the case of a 56‐year‐old woman with chronic, severe heart failure secondary to dilated cardiomyopathy and absence of significant ventricular arrhythmias who developed QT prolongation and torsade de pointes ventricular tachycardia during one cycle of intermittent low dose (2.5 mcg/kg per min) dobutamine. This report of torsade de pointes ventricular tachycardia during intermittent dobutamine supports the hypothesis that unpredictable fatal arrhythmias may occur even with low doses and in patients with no history of significant rhythm disturbances. The mechanisms of proarrhythmic effects of Dubutamine are discussed.