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Tilt Table Testing of Young Adult Patients: Improved Speed and Sensitivity Using an Isoproterenol Bolus and a Continuous 60° Tilt
Author(s) -
WALLE JEANPIERRE,
PANAGIDES DEMETRAKIS,
MESSIER MARC,
IOVESCU DECEBAL,
FOURCADE LAURENT,
BORY MICHEL,
TOUZE JEANETIENNE
Publication year - 1998
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/j.1540-8159.1998.tb00089.x
Subject(s) - medicine , tilt (camera) , bolus (digestion) , table (database) , anesthesia , mechanical engineering , data mining , engineering , computer science
The tilt table is a diagnostic device used to induce vagal syncope and determine etiology. Sensitivity enhancing techniques, such as the administration of isoproterenol, can be applied to children and young adults to compensate for the otherwise low sensitivity (20%‐30%) observed in that population. This study describes an improved test that offers a simplified approach while decreasing the amount of time involved by up to 50%, without compromising sensitivity. This 45‐minute procedure relies on sensitization with isoproterenol administered as a 2‐ to 8‐μg bolus instead of a continuous infusion. The isoproterenol is injected at the 30th minute of a 45‐minute 60° tilt test without returning the patient to the supine position. In this study, the isoproterenol bolus tilt test was found to be “positive” in 24 of 30 patients reporting unexplained syncope: 10 cases before the 30th minute (11.2 ± 8.4 min) and 14 cases after administration of 5.1 ± 1,9 μg of isoproterenol.