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Rhythmic and Electrophysiological Study After Dynamic Cardiomyoplasty
Author(s) -
RADERMECKER MARC A.,
WALEFFE ANDRÉ,
GOBIN ERIC,
GRANDJEAN PIERRE,
FOURNY JACQUES,
KULBERTUS HENRI,
LIMET RAYMOND
Publication year - 1995
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/j.1540-8159.1995.tb04736.x
Subject(s) - medicine , rhythm , electrophysiology , cardiomyoplasty , cardiology , heart rhythm , heart failure
To question the possible proarrhythrnic effects of cardiomyoplasty (CMP), six adult goats were submitted to rhythmic and electrophysiohgical (EP) study 15 days before and 8 months after a posteroanterior clockwise CMP procedure using Medtronic ± Cardiomyostimulator (CMS) (SP1005) and electrodes (SP5528) and completion of a progressive stimulation protocol. Pre and postoperative screening included a surface ECG, 24‐hour Hotter monitoring, high amplitude and filtered QRS averaging, and invasive EP study performed in the postoperative period with the CMS “ON” and “OFF.” One‐hour Hotter recording with desynchronization of the CMS was obtained. Comparison of pre and postoperative ECG and rhythmic data showed no significant difference. High amplitude QRS averaging did not evidence meeting the usual criteria of late potentials. EP values were stable in both conditions and the aggressive EP program did not show evidence of increased susceptibility to arrhythmias. Asynchronous cardiomyostimulation did not induce arrhythmias. Our data strongly suggest that provided meticulous surgical technique is used, CMP does not significantly interfere with the electrical characteristics of the normal goat heart. The procedure, despite the disturbances it provokes, does not seem to be arrhythmogenic. The function of the CMS was always appropriate, even under stressful EP conditions.