Premium
Long‐Term Clinical Performance of a Central Venous Oxygen Saturation Sensor for Rate Adaptive Cardiac Pacing
Author(s) -
FAERESTRAND SVEIN,
OHM OLEJORGEN,
STANGELAND LODVE,
HEYNEN HENRI,
MOORE ALAN
Publication year - 1994
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/j.1540-8159.1994.tb02455.x
Subject(s) - medicine , supine position , cardiology , heart rate , ventricle , oxygen saturation , anesthesia , venous blood , blood pressure , oxygen , chemistry , organic chemistry
Rate adaptive ventricular pacemakers using central venous oxygen saturation (O 2 Sat) to control the pacing rate have been implanted in 14 patients (mean age 71 years), with a mean follow‐up period of 44 months (range 2–63 months). In eight patients the pacemakers were replaced due to signs of battery depletion after an implant duration of 39–58 months. During bicycle exercise testing the O 2 Sat decreased on average from 61%± 4% at rest to 36%± 4% (P < 0,0001) at peak exercise, and the maximum pacing rate was 122 ± 5 beats/min. The time delay until the O 2 Sat bad dropped 10%, 65%, and 90% of the total reduction during exercise was 4.8 ± 0.9 seconds, 39.8 ± 3.8 seconds, and 71.3 ± 7.5 seconds, respectively. The O 2 Sat decreased 9.4%± 2% (P <0.005) from resting supine to resting sitting. Oxygen breathing increased the telemetered O 2 Sat from the pacemaker by 8.4 %± 1 % (P < 0.001). During follow‐up the O 2 Sats were relatively stable in 50% of the patients, but demonstrated significant fluctuations in the others. At 1‐year invasive follow‐up O 2 Sat measured by the pacemaker decreased 22%± 2%, and in blood samples from the right ventricle 22%± 2% from rest to 3 minutes exercise at 25 watts. There was a significant correlation between O 2 Sat measured by the pacemaker and in blood samples from right ventricle (n = 105; r = 0.73; P < 0.001). In two patients the O 2 Sat dropped significantly during pneumonia. In another patient episodes of angina pectoris was associated with low O 2 Sat and a concomitant fast pacing rate.