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Thermal Ablation of Perfused Porcine Left Ventricle In Vitro with the Neodymium‐YAG Laser Hot Tip Catheter System
Author(s) -
HAINES DAVID E.
Publication year - 1992
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/j.1540-8159.1992.tb03090.x
Subject(s) - medicine , ablation , catheter , lesion , laser , catheter ablation , ventricle , endocardium , radiofrequency ablation , biomedical engineering , nuclear medicine , surgery , cardiology , optics , physics
Catheter ablation in the treatment of arrhythmias has been limited by the small lesion size achievable with a radiofrequency energy source. The feasibility of catheter ablation with a neodymium‐yttrium‐aluminurn‐garnet (Nd‐YAG) laser hot tip catheter was tested because of the capability of achieving a high catheter‐tissue contact temperature, which should result in a larger lesion. In a model of isolated perfused pig hearts, 77 endocardial lesions were produced with powers of I to 10 watts and peak measured temperatures of 40° to 318°C. Lesion size correlated with power and temperature, but the correlations were poor. High temperature lesions resulted in significant intramyocardial catheter penetration and only marginal increased lesion width. Catheter ablation with a Nd‐YAG laser hot tip catheter is feasible, but carries a risk of perforation at high powers. High temperatures result in tissue dessication with a resultant fall in thermal conductivity that limits the radius of thermal injury and overall lesion size.