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Phase Plane Plot of Electrograms as a Marker of Ventricular Electrical Instability During Acute Ischemia: Initial Experimental Results and Potential Clinical Applications
Author(s) -
KARAGUEUZIAN HRAYR S.,
KHAN STEVEN S.,
DENTON TIMOTHY A.,
GOTOH MASAMICHI,
MANDEL WILLIAM J.,
DIAMOND GEORGE A.
Publication year - 1992
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/j.1540-8159.1992.tb03045.x
Subject(s) - medicine , cardiology , sinus rhythm , ventricular fibrillation , instability , plot (graphics) , phase plane , plane (geometry) , sinus (botany) , nonlinear system , atrial fibrillation , mechanics , physics , geometry , mathematics , statistics , quantum mechanics , botany , biology , genus
We used a phase plane plots method (a plot of voltage [V(t)] vs rate of change of voltage [dV/dt]) derived from nonlinear dynamics to transform a sinus rhythm strip into a geometric form. The geometric form thus obtained detects variations in the ECG over time and therefore may aid in identifying patterns of vulnerability to ventricular fibrillation (VF). The tralectories of consecutive ventricular depolarizations and repolarizations of sinus rhythm in dogs that evolve to VF showed characteristic differential band thickening (inhomogeneities) that were absent in the dogs that did not develop VF. This method of analysis can be a useful complementary tool to detect cardiac electrical instability, and with simple hardware, can easily be displayed in real time.