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Differences in the Pathological Changes in Dogs' Hearts After Defibrillation with Extrapericardial Paddles and Implanted Defibrillator Electrodes
Author(s) -
HARMAN DEIRDRE,
MATTHEWS ROSS,
GILLI NORMA,
MCCULLOCH ROY
Publication year - 1991
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/j.1540-8159.1991.tb05121.x
Subject(s) - paddle , medicine , ventricle , defibrillation , pericardium , necrosis , cardiology , coagulative necrosis , fissipedia , anatomy , mechanical engineering , engineering
A comparison was made between the pathological changes in the myocardium of eight dogs, each receiving about 90 joules of energy in a series of defibrillation discharges, delivered either between paddles placed against the pericardium (3 dogs) or between implanted Telectronics 040–105 defibrillation patch electrodes (5 dogs). The changes in the myocardium were most pronounced where the paddles had been applied to the pericardium. There was transmural damage beneath the left and right paddle positions and in the surrounding tissues. Extensive subepicardial and subendocardial myocyte damage was obvious histologically in the right ventricle of one of the patch dogs and in all of the paddle dogs. The percentage of damaged myocardial mass, both right ventricular and total involvement, was higher in the three paddle dogs compared with the five patch dogs. There was septal damage in the heart of one paddle dog. Necrosis of the right ventricular wall was observed in three of the patch dogs and in all the three paddle dogs. Scattered necrotic myocytes and some patches of mild necrosis up to 1‐mm deep were observed in the left ventricle of the patch dogs (severity score 1–3). The necrosis was more extensive in the paddle dogs, ranging from mild necrosis < 1‐mm deep to marked necrosis incorporating half‐to‐whole ventricular wall thickness (severity score 3–5).