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Chronic Animal Testing of New Cardiac Pacing Electrodes
Author(s) -
ADLER STEVEN,
SPEHR PAUL,
ALLEN JOHN,
BLOCK WARREN
Publication year - 1990
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/j.1540-8159.1990.tb06912.x
Subject(s) - medicine , electrode , biomedical engineering , implant , iridium , peg ratio , polyethylene glycol , electrical impedance , optoelectronics , materials science , surgery , electrical engineering , chemical engineering , biochemistry , chemistry , finance , economics , catalysis , engineering
ADLER, S., ET AL.: Chronic Animal Testing of New Cardiac Pacing Electrodes. To evaluate the electrical performance of new electrode technologies, 24 leads containing either carbon coated porous titanium (BIOPORE, (Intermedics, Inc., Freeport, TX)), iridium oxide (IROX), or iridium oxide coated with polyethylene glycol (IROX‐PEG) electrodes (eight of each) were implanted into the ventricles of 12 canines. Stimulation threshold data was measured at regular intervals for 24 weeks. Low acute values were observed for all leads (0.32 ± 13 V at 0.6 msec pulse width), but the IROX‐PEG electrode demonstrated lower subchronic, peak, and chronic values. Compared to implant, the IROX‐PEG electrodes' stimulation thresholds rose only 0.23 V when chronic conditions occurred. There were no significant differences between the electrodes in pacing impedance or R wave amplitude measurements. We conclude that both IROX and IROX‐PEG technologies represent a promising approach to the design of more efficient cardiac pacing leads.