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Normal Myocardial Enzymes and Normal Echocardiographic Findings During Noninvasive Transcutaneous Pacing
Author(s) -
MADSEN JAN KYST,
PEDERSEN FLEMMING,
GRANDE PEER,
MEIBOM JØRGEN
Publication year - 1988
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/j.1540-8159.1988.tb03971.x
Subject(s) - medicine , cardiology , creatine kinase , myoglobin , lactate dehydrogenase , heart rate , anesthesia , blood pressure , enzyme , biochemistry , chemistry , organic chemistry
Noninvasive transcutaneous pacing was performed for 30 minutes in 10 healthy volunteers. The pace rate was from 85 to 115 min, 1 and the threshold for pacing was from 38 to 70 mA, median 59 mA. Echocardiography before and during pacing showed no changes in left ventricular end‐diastolic diameter, in fractional shortening nor in contraction pattern. Also, hood pressure remained unchanged. Blood samples for determination of myoglobin, creatine phosphokinase, creatine kinase MB and lactate dehydrogenase were drawn prior to pacing and 1,2,3,4,6,8 and 24 hours after pacing. The serum concentrations were the same before and after pacing for all enzymes and myoglobin. We conclude that non‐invasive transcutaneous pacing for 30 minutes causes no muscular or myocardial injury and that the left ventricular function remains normal.