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Possible Proarrhythmic Effects of Tocainide in Dilated Cardiomyopathy
Author(s) -
BROWNSTEIN SHELDON L.,
CONSTANTIN LUIS,
KIENZLE MICHAEL G.,
MARTINS JAMES B.
Publication year - 1988
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/j.1540-8159.1988.tb03948.x
Subject(s) - medicine , cardiology , ventricular tachycardia , ventricular fibrillation , dilated cardiomyopathy , myocardial infarction , asymptomatic , proarrhythmia , tachycardia , anesthesia , atrial fibrillation , heart failure
A patient with a dilated cardiomyopaphy experienced a cardiac arrest when taking tocainide for asymptomatic nonsustained ventricular tachycardia. After successful resuscitation from ventricular fibrillation and exclusion of a myocardial infarction, an electrophysiological evaluation was performed. Drug‐free study #1 revealed no induction of ventricular tachycardia. A tocainide study revealed induction of sustained monomorphic ventricular tachycardia. Drug‐free study #2 revealed induction of nonsustained ventricular tachycardia. This report illustrates a possible proarrhythmic effect of tocainide.