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Dorsal Periaqueductal Gray‐Matter Stimulation in Humans
Author(s) -
HOSOBUCHI YOSHIO
Publication year - 1987
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/j.1540-8159.1987.tb05951.x
Subject(s) - medicine , stimulation , periaqueductal gray , dorsum , anesthesia , deep brain stimulation , central nervous system , anatomy , midbrain , disease , parkinson's disease
Seven patients suffering intractable pain from head and neck cancer (age 48–73, mean 57.5 years) underwent acute stimulation of dorsal periaqueductal gray matter (PAG) with immediate cessation of pain. Two patients received chronic PAG stimulation with relief of pain during stimulation. The effect was not reversed by naloxone and there were no changes in CSF peptides.