Premium
Rate‐Responsive Ventricular Pacing: Clinical Experience With the RS4‐SRT Pacing System
Author(s) -
RAMSDALE DAVID R.,
CHARLES RICHARD G.
Publication year - 1985
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/j.1540-8159.1985.tb05775.x
Subject(s) - medicine , cardiac pacing , ventricular pacing , cardiology , anesthesia , heart failure
Eighteen patients (11 men and 7 women) with symptomatic second or third degree atrioventricular block underwent implantation of the rate‐responsive RS4‐SRT pacing system. Exercise tolerance in RS4 mode was compared to that in VVI mode by randomized double‐blind treadmill stress testing. Following hospital discharge, HS4 function was assessed by repeat exercise testing and 24‐hour Holter monitoring. Difficulty in obtaining satisfactory P‐wave amplitudes at implonfation (mean 3.1 ±1.5 mV) resulted in prolonged implantation times (mean 79.4 ± 26.4 minutes). Following implantation, 10 patients (58%) showed a significant ventricular rate response to exercise, seven did not, and one remained in sinus rhythm. For responders, peak ventricular paced rate and double product were significantly greater in RS4 than in VVI mode, being 101.8 ± 5.8 vs. 74.3 ± 0.4 beats per minute and 20.1 ± 2.9 vs. 15.5 ± 3.7 beats per minute ± mmHg ± 10 −3 , respectively (p < 0.001). However, treadmill times (10.5 ± 2.6 vs. 9.7 ± 3.3 minutes) and work done (5.51 ± 2.01 vs. 4.97 ± 2.33 joules ± 10 −5 ) were not significantly different (p = 0.22). Following hospital discharge, repeat exercise testing and 24‐hour Holter monitoring demonstrated RS4 junction in 11 of 16 and 15 of 18 patients, respectively. We conclude that, due to unreliable atrial sensing, the RS4‐SRT pacing system does not provide the reliable rate‐responsiveness required to improve exercise tolerance.