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Mixed Carotid Sinus Hypersensitivity: Successful Therapy with Pacing, Ephedrine, and Propranolol
Author(s) -
KEATING EDWARD C.,
BURKS JOHN M.,
CALDER JOSEPH R.
Publication year - 1985
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/j.1540-8159.1985.tb05770.x
Subject(s) - medicine , propranolol , ephedrine , carotid sinus , anesthesia , inhibitory postsynaptic potential , cardiac pacing , cardiology , intensive care medicine , reflex
Three forms of carotid sinus hypersensitivity are recognized clinically (cardio‐inhibitory, vasodepressor, and mixed). The cardio‐inhibitory form has been managed successfully with pacemaker therapy. The vasodepressor element has been difficult to manage clinically whether in its pure form or in combination with the cardio‐inhibitory type. We review the various pharmacologic methods previously reported and present our experience with a new pharmacologic alternative, which is the combined use of ephedrine and propranolol to induce unopposed alpha stimulation.