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The Electrophysiological Substrate of Atrial Fibrillation
Author(s) -
SIMPSON ROSS J.,
FOSTER JAMES R.,
MULROW JOHN P.,
GETTES LEONARD S.
Publication year - 1983
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/j.1540-8159.1983.tb04454.x
Subject(s) - medicine , electrophysiology , atrial fibrillation , refractory period , cardiology , effective refractory period , atrium (architecture) , autonomic nervous system , electrical conduction system of the heart , fibrillation , electrocardiography , heart rate , blood pressure
The electrophysiological substrate that predisposes the human atrium to sustain alrial fibrillation is incompletely understood. However, abnormalities of atrial size, refractory period and conduction are important precursors to this arrhythmia. The propensity of various disease states, cardio active drugs and the autonomic nervous system to potentiate atrial fibrillation may be explained by changes in these electrophysiological properties.
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