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TQ Segment (Baseline) Alternans during PrinzmetaPs Variant Angina
Author(s) -
ROZANSKI JOHN J.,
KLEINFELD MORRIS
Publication year - 1980
Publication title -
pacing and clinical electrophysiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.686
H-Index - 101
eISSN - 1540-8159
pISSN - 0147-8389
DOI - 10.1111/j.1540-8159.1980.tb05577.x
Subject(s) - medicine , cardiology , repolarization , ventricular tachycardia , angina , ventricular fibrillation , st segment , depolarization , myocardial infarction , electrophysiology
In a study of 93 patients who met criteria for Prinz‐metal's angina, alternans of the ST segment was observed in 28 of 93 patients (30%), In 8 of these 28 patients, a hitherto undescribed variant of alternans, namely alternation (≥1 mm shift in 2:1 pattern) in the amplitude of the baseline or TQ segment (TQ AI) was observed. In all eight patients serious ventricular arrhythmias were noted, namely, ventricular fibrillation in two, ventricular tachycardia in four, and multiform or advanced ventricular ectopic activity in eight. The TQ All developed only after ST segment alternans occurred. It is postulated that the alternations of the ST and TQ segments are due to differences in current flows due lo inhomogeneity of depolarization and repolarization of the action potential caused by ischemia. Furthermore, the associated arrhythmias observed are related to the inhomo‐geneous state initiated by the ischemia.