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Transmissible Spongiform Encephalopathy Risk Assessment: The UK experience
Author(s) -
Grist Eric P. M.
Publication year - 2005
Publication title -
risk analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.972
H-Index - 130
eISSN - 1539-6924
pISSN - 0272-4332
DOI - 10.1111/j.1539-6924.2005.00619.x
Subject(s) - bovine spongiform encephalopathy , estimation , risk assessment , transmissible spongiform encephalopathy , identification (biology) , environmental health , medicine , disease , risk analysis (engineering) , prion protein , biology , computer science , computer security , pathology , engineering , scrapie , botany , systems engineering
Transmissible spongiform encephalopathy (TSE) risk assessments undertaken in the United Kingdom have mainly had the objective of determining the risks posed to humans from exposure to the causal agents associated with bovine spongiform encephalopathy (BSE) and variant Creutzfeld‐Jakob disease (vCJD). In this article, I examine 19 of these risk assessments published to date and consider how their results might be influenced by underlying model assumptions and methodology. Three separate aspects common to all the assessments are infective load estimation, exposure pathway identification, and risk estimation. These are each discussed in detail.

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