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Time‐ and Loading‐Dependence in the McKone Model for Dermal Uptake of Organic Chemicals from a Soil Matrix
Author(s) -
Burmaster David E.,
Maxwell Nancy Irwin
Publication year - 1991
Publication title -
risk analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.972
H-Index - 130
eISSN - 1539-6924
pISSN - 0272-4332
DOI - 10.1111/j.1539-6924.1991.tb00634.x
Subject(s) - matrix (chemical analysis) , function (biology) , organic chemicals , biological system , plot (graphics) , fraction (chemistry) , environmental science , environmental chemistry , soil science , chemistry , mathematics , statistics , organic chemistry , chromatography , biology , evolutionary biology
McKone has recently proposed an innovative two‐layer model for dermal uptake of organic chemicals from a soil matrix that explicitly includes variables for properties of the chemical, the soil, the skin, and the exposure. In this note, we investigate the joint time‐ and loading‐dependencies implicit in the model by using MATHEMATICA to find and plot a closed‐form function for the uptake fraction for six aromatic hydrocarbons.