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Chemical Scoring by a Ra pid Screening of H azard (RASH) Method
Author(s) -
Jones Troyce D.,
Walsh Phillip J.,
Watson Annette P.,
Owen Bruce A.,
Barnthouse Larry W.,
Sanders Dee A.
Publication year - 1988
Publication title -
risk analysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.972
H-Index - 130
eISSN - 1539-6924
pISSN - 0272-4332
DOI - 10.1111/j.1539-6924.1988.tb01157.x
Subject(s) - potency , hazardous waste , rash , toxicology , hazard , cas registry number , chemical safety , chemistry , engineering , medicine , biochemical engineering , biology , toxicity , waste management , organic chemistry , biochemistry , in vitro
A ra pid screening of h azard method (RASH) is presented for deriving relative potency estimates for hazardous substances. The method utilizes data from any available toxicological database such as the Registry of Toxic Effects of Chemical Substances (RTECS) or EPA's GENE‐TOX database on genetic activity profiles. The method has been applied to derive relative potency values and permissible environmental concentrations for 278 chemicals. The derived values have been compared with recommendations of expert committees where possible, and substantial agreement is found.