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Metabolic pathways: does the actual Gibbs free‐energy change affect the flux rate?
Author(s) -
Aledo J. Carlos
Publication year - 2001
Publication title -
biochemistry and molecular biology education
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.34
H-Index - 39
eISSN - 1539-3429
pISSN - 1470-8175
DOI - 10.1111/j.1539-3429.2001.tb00100.x
Subject(s) - flux (metallurgy) , gibbs free energy , function (biology) , metabolic pathway , affect (linguistics) , metabolic rate , energy (signal processing) , energy metabolism , dissipation , thermodynamics , chemistry , physics , metabolism , biology , biochemistry , mathematics , statistics , psychology , microbiology and biotechnology , endocrinology , organic chemistry , communication
Energy dissipation fulfils an important function in metabolism driving the flux of matter through metabolic pathways. The flux rate is a multivariable function. One of such variables affecting the flux is the actual free energy change. A particular case of metabolic pathway is analysed to illustrate this fact, using only general enzymic and thermodynamic concepts. © 2001 IUBMB. Published by Elsevier Science Ltd. All rights reserved.