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Intermittent mechanical compression for prevention of travellers’ thrombosis
Author(s) -
COPPENS M.,
VAN DOORMAAL F. F.,
SCHREIJER A. J. M.,
ROSENDAAL F. R.,
BÜLLER H. R.
Publication year - 2006
Publication title -
journal of thrombosis and haemostasis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.947
H-Index - 178
eISSN - 1538-7836
pISSN - 1538-7933
DOI - 10.1111/j.1538-7836.2006.02019.x
Subject(s) - medicine , intermittent pneumatic compression , thrombosis , deep vein , pulmonary embolism , venous thrombosis , compression stockings , antithrombotic , surgery , concomitant , anesthesia , cardiology
CONCLUSIONS • Absolute incidence of airtravel related venous thromboembolism is estimated to be approximately 1 / 5000 for flights lasting >4 hours • This risk is higher in people with additional risk factors such as oral contraceptive use, inherited thrombophilia and high age • Intermittent pneumatic compression reduces the risk of postoperative VTE by increasing venous outflow, and possibly by increasing fibrinolytic activity • 6 healthy volunteers, aged over 55 years • 4 hours of strict seated immobilisation • 2 test days: one without and one with intermittent mechanical compression (IMC) • IMC exerted by a novel lightweight device (AviafitTM, FlowMedic, Israel), placed on both calves, generating 1 pulse / minute of 45 mmHg • Outcome: Venous outflow (Duplex US), Lower extremity volume (waterbath), laboratory markers of coagulation/fibrinolysis