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Is aspirin effective in diabetic patients? Yes
Author(s) -
COLWELL J. A.
Publication year - 2005
Publication title -
journal of thrombosis and haemostasis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.947
H-Index - 178
eISSN - 1538-7836
pISSN - 1538-7933
DOI - 10.1111/j.1538-7836.2005.01719.x
Subject(s) - aspirin , medicine , diabetes mellitus , disease , clinical trial , myocardial infarction , randomized controlled trial , intensive care medicine , endocrinology
The critical word in this question is effective. Webster defines effective in several ways: • Having an effect; producing a result. • Producing a definite or desired result. • Making a striking impression. There is evidence that aspirin is effective in reducing the risk of myocardial infarction in people with diabetes. There is also evidence that aspirin therapy has been effective in making a striking impression. This has let to firm guidelines for its use in people with elevated cardiovascular risk. We will consider four major issues in developing the argument that aspirin is effective in diabetic patients. 1 What is the pathophysiologic rationale for prescribing aspirin to reduce cardiovascular risk in diabetic patient? 2 What is the cardiovascular risk for people with diabetes? 3 What do controlled clinical trials indicate regarding the effectiveness of aspirin in reducing the risk for myocardialinfarction? 4 What are the guidelines for the use of aspirin in diabetic individuals and others at high cardiovascular risk?