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The development of atypical hemolytic uremic syndrome is not influenced by thrombophilia susceptibility factors
Author(s) -
KEMP E. J.,
STRAIN L.,
DIAZTORRES M. L.,
GOODSHIP J. A.,
GOODSHIP T. H. J.
Publication year - 2005
Publication title -
journal of thrombosis and haemostasis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.947
H-Index - 178
eISSN - 1538-7836
pISSN - 1538-7933
DOI - 10.1111/j.1538-7836.2005.01548.x
Subject(s) - atypical hemolytic uremic syndrome , thrombophilia , medicine , immunology , thrombosis , antibody , complement system
usually developed progressive pneumonia with acute respiratory distress syndrome and consequently died. Hemostatic disorders could also be seen in those infected cases [1]. Many laboratory aberrations are noted in the cases with bird flu. Thrombocytopenia is usually noted in the severe bird flu infection [2]. Here, the author performed this mini study in order to document the impact of bird flu infection on prothrombin time (PT) among reported Thai patients. A literature review on the papers concerning human bird flu in Thailand was performed. The author performed the literature review on human bird flu infection reports in Thailand from the database of published works cited in the Index Medicus and Science Citation Index. The author also reviewed the published works in all 256 local Thai journals, which is not included in the international citation index, for the report of human bird flu infection in Thailand. The reports that contained no complete data were excluded for further analysis. According to this review, there are six reports [3–8] covering 12 Thai patients with confirmed diagnosis of bird flu. Of interest, prolonged PT is reported in no case. Although some researchers proposed that the prolonged PT should be a common finding in the patients with bird flu [9], the finding in this study argued against that proposal. The bleeding presentation in the patients with bird flu should relate to the pathology of platelet rather than prolonged PT.