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Core temperature changes in resuspended red blood cells (RBCs) and pediatric RBCs removed from refrigerated storage
Author(s) -
Perry Holly Elizabeth,
Prasad Priyanka,
Kirwan Susy,
Huang Yuan Qing
Publication year - 2010
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/j.1537-2995.2009.02384.x
Subject(s) - core temperature , blood preservation , medicine , core (optical fiber) , anesthesia , zoology , chemistry , andrology , materials science , biology , composite material
BACKGROUND: The 30‐minute rule, whereby intact red blood cell (RBC) products may be returned to stock if returned to 4°C storage within 30 minutes of issue, was established many years ago. It was based on observations that the core temperature of units of whole blood removed from storage temperatures of 1 to 6°C, and left at room temperature, would reach 10°C at between 45 minutes and 1 hour. STUDY DESIGN AND METHODS: Forty‐one units of RBCs resuspended leukoreduced and 8 units of pediatric RBCs resuspended leukoreduced were exposed to ambient temperature for periods of time between 0 and 60 minutes. Core temperatures of all units were measured at 1‐minute or 5‐minute intervals. RESULTS: Resuspended RBCs units reached a mean core temperature of 10°C at 15 minutes, 12.7°C at 30 minutes, and 15°C at 60 minutes. Pediatric RBCs reached a mean core temperature of 12.8°C at 15 minutes, 15.5°C at 30 minutes, and 17.8°C at 60 minutes. CONCLUSION: In view of our results, and the range of RBC products now available, it may be timely for blood services to review and reduce the 30‐minute rule.