Premium
Plasmapheresis in asparaginase‐induced hypertriglyceridemia
Author(s) -
KfouryBaz Elizabeth M.,
Nassar Rabih A.,
Tanios Rita F.,
Otrock Zaher K.,
Youssef Amira M.,
Albany Costantine,
Bazarbachi Ali,
Salem Ziad M.
Publication year - 2008
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/j.1537-2995.2008.01663.x
Subject(s) - plasmapheresis , hypertriglyceridemia , medicine , asparaginase , lymphoblastic leukemia , pancreatitis , acute pancreatitis , chemotherapy , lymphoblastic lymphoma , gastroenterology , leukemia , triglyceride , immunology , cholesterol , immune system , t cell , antibody
BACKGROUND: Asparaginase is an essential component of the chemotherapy regimens during the induction and intensification phases for acute lymphoblastic leukemia and lymphoblastic lymphoma. The administration of asparaginase can cause elevation of the triglyceride levels. CASE REPORT: This study reports the case of an adult patient presenting with acute pancreatitis secondary to severe hypertriglyceridemia after asparaginase treatment during the consolidation phase of lymphoblastic lymphoma. This condition was successfully treated with plasmapheresis. CONCLUSIONS: Our case demonstrates that plasmapheresis in severe cases of hypertriglyceridemia offers a safe and efficient treatment option for symptomatic patients.