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Storage, Rejuvenation, and Restorage of Human Red Cells for Periods up to 56 Days
Author(s) -
Moore G. L.,
Failla M. L.,
Blake B. H.,
Gray J. L.,
Manalo F. W.
Publication year - 1974
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/j.1537-2995.1974.tb04525.x
Subject(s) - rejuvenation , blood preservation , andrology , red blood cell , human blood , biology , medicine , zoology , immunology , physiology , surgery
Human red blood cells may be stored at 4 C for periods up to 56 days and then successfully rejuvenated. The rejuvenated red blood cells have nearly normal levels of ATP and 2,3‐DPG and retain these elevated levels for at least four days following rejuvenation. This greatly increases the usefulness of stored red blood cells, both in terms of reclaiming the red blood cells for freezing and in rejuvenation to extend the period of 4 C stored blood to 42 or 56 days.