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Procurement and Identification of HL‐A Lymphocytotoxic Antibodies in Sera of Nonpregnant, Multiparous Blood Donors
Author(s) -
Rodey G. E.,
Kunicki J.,
Anderson J.,
Aster R. H.
Publication year - 1974
Publication title -
transfusion
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.045
H-Index - 132
eISSN - 1537-2995
pISSN - 0041-1132
DOI - 10.1111/j.1537-2995.1974.tb04511.x
Subject(s) - plasmapheresis , antibody , medicine , titer , population , blood donor , apheresis , immunology , platelet , environmental health
An efficient procedure for large‐scale screening of nonpregnant multiparous blood donor sera is described. Yield of useful HL‐A reagents in this population compares favorably to yields obtained from screening pregnant women near term. The advantages of screening nonpregnant donors include stable antibody titers, ease of procurement, and the willingness of voluntary blood donors to return for plasmapheresis.